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G J Sanger Selected Research

Constipation

2/2014Ghrelin and motilin receptor agonists: time to introduce bias into drug design.
12/2009Translating 5-HT receptor pharmacology.
1/2009Oral administration of a centrally acting ghrelin receptor agonist to conscious rats triggers defecation.
5/2008Activation of prostaglandin EP receptors by lubiprostone in rat and human stomach and colon.
10/2004The role of endogenous opioids in the control of gastrointestinal motility: predictions from in vitro modelling.
6/2000Increased defecation during stress or after 5-hydroxytryptophan: selective inhibition by the 5-HT(4) receptor antagonist, SB-207266.

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G J Sanger Research Topics

Disease

6Constipation
02/2014 - 06/2000
5Nausea
02/2014 - 01/2006
3Gastroparesis
02/2014 - 06/2010
3Vomiting
06/2008 - 09/2006
3Anorexia
06/2008 - 01/2006
3Neoplasms (Cancer)
06/2008 - 01/2006
3Pain (Aches)
11/2007 - 12/2001
2Gastroesophageal Reflux (GERD)
09/2014 - 11/2007
2Dyspepsia (Indigestion)
06/2008 - 09/2006
2Inflammation (Inflammations)
11/2007 - 08/2003
2Neuralgia (Stump Neuralgia)
11/2001 - 01/2000
1Obesity
06/2019
1Overweight
06/2019
1Weight Loss (Weight Reduction)
06/2019
1Alzheimer Disease (Alzheimer's Disease)
11/2013
1Colonic Pseudo-Obstruction (Ogilvie Syndrome)
11/2013
1Stomach Neoplasms (Stomach Cancer)
12/2012
1Stroke (Strokes)
07/2009
1Movement Disorders (Movement Disorder)
06/2009
1Crohn Disease (Crohn's Disease)
01/2009
1Gastritis
11/2007
1Body Weight (Weight, Body)
11/2007
1Fatigue
01/2006
1Hypersensitivity (Allergy)
08/2003

Drug/Important Bio-Agent (IBA)

5GhrelinIBA
02/2014 - 09/2006
2MotilinIBA
09/2014 - 02/2014
2Erythromycin (Erycette)FDA LinkGeneric
02/2014 - 06/2009
2Serotonin (5 Hydroxytryptamine)IBA
06/2009 - 06/2000
2Ghrelin ReceptorsIBA
01/2009 - 06/2008
2Messenger RNA (mRNA)IBA
11/2001 - 01/2000
1Protein Isoforms (Isoforms)IBA
06/2019
1Bile Acids and Salts (Bile Acids)IBA
06/2019
1LigandsIBA
02/2014
1Donepezil (Aricept)FDA LinkGeneric
11/2013
15-HT4 Serotonin ReceptorsIBA
11/2013
1prucaloprideIBA
11/2013
1Cholinesterase Inhibitors (Anticholinesterases)IBA
11/2013
1Neostigmine (Neostigmine Bromide)IBA
11/2013
1TD-5108IBA
12/2009
1ATI 7505IBA
12/2009
15-hydroxyindalpineIBA
07/2009
1Metoclopramide (Reglan)FDA LinkGeneric
06/2009
1Anti-Bacterial Agents (Antibiotics)IBA
06/2009
1Infliximab (Remicade)FDA Link
01/2009
1ChloridesIBA
05/2008
1LubiprostoneFDA Link
05/2008
1ProstaglandinsIBA
05/2008
1CLC-2 Chloride ChannelsIBA
05/2008
1CannabinoidsIBA
11/2007
1AntiemeticsIBA
11/2007
1EndocannabinoidsIBA
11/2007
1CB1 Cannabinoid Receptor (CB1 Receptor)IBA
11/2007
1CB2 Cannabinoid ReceptorIBA
11/2007
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
07/2007
1Cisplatin (Platino)FDA LinkGeneric
01/2006
1Opioid Receptors (Opioid Receptor)IBA
10/2004
1SB 223412IBA
08/2003
1Capsaicin (Zostrix)FDA Link
12/2001
1Calcium Channels (Calcium Channel)IBA
11/2001
1sterile 20-like protein kinase nerve injury-associated kinaseIBA
01/2000
1RNA (Ribonucleic Acid)IBA
01/2000
1Protein Kinases (Protein Kinase)IBA
01/2000

Therapy/Procedure

3Drug Therapy (Chemotherapy)
06/2008 - 01/2006
2Ligation
11/2001 - 01/2000
1Gastrectomy
06/2019
1Enteral Nutrition (Feeding, Tube)
12/2013
1Adjuvant Chemotherapy
12/2012
1Therapeutics
06/2009
1Oral Administration
01/2009